Lineage classification and antitubercular drug resistance surveillance of Mycobacterium tuberculosis by whole-genome sequencing in Southern India

ABSTRACT Whole-genome sequencing has created a revolution in tuberculosis management by providing a comprehensive picture of the various genetic polymorphisms with unprecedented accuracy.Studies mapping genomic heterogeneity in clinical isolates of Mycobacterium tuberculosis using a whole-genome sequencing approach from high tuberculosis burden cou

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Long term steroid metabolism balance studies in subjects on cholesterol-free and cholesterol-rich diets: comparison between normal and hypercholesterolemic individuals

Regulation of cholesterol metabolism was investigated in eight hypercholesterolemic and five normal individuals by combined intravenous pulse-labeling with radioactive cholesterol and fecal steroids balance techniques.Mean serum cholesterol concentrations ranged from 168 to 717 mg/dl.Experiments were scheduled in the following sequence: a cholester

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Is physician supervision of the capsaicin 8% patch administration procedure really necessary? An opinion from health care professionals

Kai-Uwe Kern,1 Janice England,2 Andrea Roth-Daniek,3 Till Wagner3 1Institute for Pain Medicine/Pain Practice, Wiesbaden, Germany; 2Pain Medicine and Anaesthesia, The Christie National Health Service Foundation Trust, Manchester, UK; 3Pain Therapy and Palliative Care Department, Medizinisches Zentrum Städteregion Aachen, Aachen, Germany Abstrac

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